ANKMJ
Ankyra Medical Journal

Ankyra Medical Journal (AnkMJ), formerly known as the Journal of Translational and Practical Medicine, regularly publishes international quality issues in the field of Medicine in the light of current information.

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Original Article
The association between fibrocystic breast and thyroid autoimmunity
Abstract
Aims: The relationship between thyroid disorders and breast diseases including breast cancer and benign breast disease, has been a topic of interest and controversy. Our study aimed to investigate the potential association between autoimmune thyroid disease (ATD) and fibrocystic breast disease (FBD)
Methods: This retrospective study investigated the relationship between atd an FBD. A total of 242 female patients aged 18 years or older were recruited for the study. Data were collected from medical records and patient interviews. The related parameters were recorded for each participant.
Results: This study included two hundred forty-two age-matched (29.78±4.55) and body mass index (BMI)-matched (24±2.38) women. A Mann-Whitney test did not find a statistically significant association between the case and control in terms of Free thyroxine (FT4) (p-value>0.05). There was a statistically significant difference between groups in terms of thyroid-stimulating hormone (TSH) (p-value<0.001), antithyroid peroxidase (Anti-TPO) (p-value<0.001), and anti-thyroglobulin (Anti-TG) (p-value<0.001). A chi-square test did not find a statistically significant association between thyroid autoantibody and fibrocystic breast test results (p-value > 0.05).
Conclusion: While our study did not find a significant association between these two conditions, other studies have reported varying results. Hormonal alterations, autoimmune factors, and genetic predispositions are among the potential mechanisms that could explain the associations observed in some studies.

Keywords : Autoimmune thyroid disease, thyroid disorders, fibrocystic breast, thyroid autoimmunity, risk factors

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Article available in :
Volume 2, Issue 2, 2023
Page : 36-40
https://doi.org/10.51271/JTPM-0038
Article Information
Received : 12 Tem 2023
Accepted : 25 Tem 2023
Published : 31 Ağu 2023
Corresponding Author :

Asena Ayar Madenli: Department of Obstetrics and Gynecology, Liv Hospital Vadİstanbul, İstanbul, Turkiye

[email protected]
Citation : Çetiner S, Ayar Madenli A, Çalı Öztürk H. The association between fibrocystic breast and thyroid autoimmunity. J Transl Pract Med. 2023;2(2):36-40.

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